IRAK1

IRAK1
interleukin-1 receptor-associated kinase 1
Обозначения
Символы IRAK1
Entrez Gene 3654
HGNC 6112
OMIM 300283
RefSeq NM_001025242
UniProt P51617
Другие данные
Локус X-хр., Xq28
Активация липополисахаридным рецепторным комплексом CD14/TLR4/MD2 фактора трансрипции NFkB.

IRAK1 (англ. interleukin-1 receptor-associated kinase 1) — цитозольная киназа, относящаяся к группе IRAK. Участвует в передаче сигнала от рецептора интерлейкина-1 (тип I) и некоторых толл-подобных рецепторов. Содержит магний в качестве кофактора. Открыта в 1996 году.

См. также

Литература

  • Ringwood L, Li L (April 2008). «The involvement of the interleukin-1 receptor-associated kinases (IRAKs) in cellular signaling networks controlling inflammation». Cytokine 42 (1): 1–7. DOI:10.1016/j.cyto.2007.12.012. PMID 18249132.


Звезда жизни

Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать курсовую

Полезное


Смотреть что такое "IRAK1" в других словарях:

  • IRAK1 — Interleukin 1 receptor associated kinase 1, also known as IRAK1, is a human gene. PBB Summary section title = summary text = This gene encodes the interleukin 1 receptor associated kinase 1, one of two putative serine/threonine kinases that… …   Wikipedia

  • Blutkind — Infobox Album | Name = Bunkertor 7 Type = Album Artist = Released = 2000 | Recorded = 2000 Genre = Industrial Length = 2:10:15 Label = Beton Kopf Media Producer = Rudy Ratzinger Reviews = Last album = Eevil Young Flesh (1999) This album =… …   Wikipedia

  • IRAK2 — interleukin 1 receptor associated kinase 2 Обозначения Символы IRAK2 Entrez Gene …   Википедия

  • MYD88 — Myeloid differentiation primary response gene (88) Signaling pathway of toll like receptors. Dashed grey lines represent unknown associations …   Wikipedia

  • Signal transduction — In biology, signal transduction refers to any process by which a cell converts one kind of signal or stimulus into another. Most processes of signal transduction involve ordered sequences of biochemical reactions inside the cell, which are… …   Wikipedia

  • Protein kinase A — In cell biology, Protein kinase A (PKA) refers to a family of enzymes whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA is also known as cAMP dependent protein kinase (EC 2.7.11.11). Protein kinase A has several functions… …   Wikipedia

  • Small GTPase — Small GTPases are a family of hydrolase enzymes that can bind and hydrolyze guanosine triphosphate (GTP). They are a form of G proteins found in the cytosol which are homologous to the alpha subunit of heterotrimeric G proteins, but unlike the… …   Wikipedia

  • Toll-like receptor — Toll like receptors (TLRs) are a class of single membrane spanning non catalytic receptors that recognize structurally conserved molecules derived from microbes once they have breached physical barriers such as the skin or intestinal tract mucosa …   Wikipedia

  • Dancon/Irak — is short for Danish Contingent/Irak , and was the designated name for the Danish ground contingent deployed to Iraq from June 2003 to July 2007.HistoryDancon s units were subordinate to Multi National Division (South East) ( MND(SE) ), which is… …   Wikipedia

  • Protein tyrosine phosphatase — Protein tyrosine phosphatases (PTPs) are a group of enzymes that remove phosphate groups from phosphorylated tyrosine residues on proteins. Protein tyrosine (pTyr) phosphorylation is a common post translational modification that can create novel… …   Wikipedia


Поделиться ссылкой на выделенное

Прямая ссылка:
… Нажмите правой клавишей мыши и выберите «Копировать ссылку»