Akt/PKB signaling pathway

Akt/PKB signaling pathway

The Akt/PKB signaling pathway is a pathway in cell signaling.cite journal |author=Song G, Ouyang G, Bao S |title=The activation of Akt/PKB signaling pathway and cell survival |journal=J. Cell. Mol. Med. |volume=9 |issue=1 |pages=59–71 |year=2005 |pmid=15784165 |doi= |url=http://www.blackwell-synergy.com/openurl?genre=article&sid=nlm:pubmed&issn=1582-1838&date=2005&volume=9&issue=1&spage=59]

Proteins involved include AKT (also known as "protein kinase B") and phosphoinositide 3-kinase.

It can be associated with cancer.cite journal |author=DeFeo-Jones D, Barnett SF, Fu S, "et al" |title=Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members |journal=Mol. Cancer Ther. |volume=4 |issue=2 |pages=271–9 |year=2005 |month=February |pmid=15713898 |doi= |url=http://mct.aacrjournals.org/cgi/pmidlookup?view=long&pmid=15713898]

References


Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • AKT — protein Name=v akt murine thymoma viral oncogene homolog 1 caption= width= HGNCid=391 Symbol=AKT1 AltSymbols= EntrezGene=207 OMIM=164730 RefSeq=NM 005163 UniProt=P31749 PDB= ECnumber= Chromosome=14 Arm=q Band=32.32 LocusSupplementaryData=… …   Wikipedia

  • Notch signaling pathway — Structure of the ligand binding region of the human NOTCH 1 receptor …   Wikipedia

  • Signaling molecule — A signaling molecule is a chemical involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another… …   Wikipedia

  • Epidermal growth factor receptor — This article is about a cell surface receptor. For estimated measure of kidney function (eGFR), see Glomerular filtration rate. Epidermal growth factor receptor …   Wikipedia

  • c-Met — Met proto oncogene (hepatocyte growth factor receptor) Crystallographic structure of MET. PDB rendering based on 1r0p …   Wikipedia

  • ERBB3 — V erb b2 erythroblastic leukemia viral oncogene homolog 3 (avian) PDB rendering based on 1m6b …   Wikipedia

  • Mothers against decapentaplegic homolog 4 — SMAD family member 4 PDB rendering based on 1dd1 …   Wikipedia

  • Mothers against decapentaplegic homolog 2 — SMAD family member 2 PDB rendering based on 1dev …   Wikipedia

  • CDKN1B — Cyclin dependent kinase inhibitor 1B (p27, Kip1) PDB rendering based on 1jsu …   Wikipedia

  • c-Fos — FBJ murine osteosarcoma viral oncogene homolog PDB rendering based on 1a02 …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”