Substantia gelatinosa of Rolando

Substantia gelatinosa of Rolando

Infobox Anatomy
Name = PAGENAME
Latin = substantia gelatinosa cornu posterioris medullae spinalis
GraySubject = 185
GrayPage = 753


Caption = Substantia gelatinosa of Rolando is Rexed lamina II, labeled at upper left.


Caption2 =
System =
Precursor =
MeshName = Substantia+Gelatinosa
MeshNumber = A08.186.854.610.800
DorlandsPre = s_27
DorlandsSuf = 12766752
The apex of the posterior horn of the gray matter of the spinal cord is capped by a V-shaped or crescentic mass of translucent, gelatinous neuroglia, termed the substantia gelatinosa of Rolando (or gelatinous substance of posterior horn of spinal cord), which contains both neuroglia cells, and small nerve cells. The gelatinous appearance is due to a very low concentration of myelinated fibers.

It is named for Luigi Rolando.

It corresponds to Rexed lamina II.

Function

Many μ- and к-opioid receptors, presynaptic and postsynaptic, are found on these nerve cells; they can be targeted to manage pain of distal origin.

C fibers terminate at this layer.

External links

*
* [http://thalamus.wustl.edu/course/body3.gifDiagram] at Washington University in St. Louis

It is not known, however, if cocaine acts on this pathway.


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