Panniculitis

Panniculitis
Panniculitis
Classification and external resources
ICD-10 M79.3
ICD-9 729.3
DiseasesDB 29081
MeSH D015434

Panniculitis is a group of diseases whose hallmark is inflammation of subcutaneous adipose tissue (the fatty layer under the skin - panniculus adiposus).[1] Symptoms include tender skin nodules, and systemic signs such as weight loss and fatigue.

Restated, an inflammatory disorder primarily localized in the subcutaneous fat is termed a "panniculitis," a group of disorders that may be challenging both for the clinician and the dermatopathologist.[2]:487

Contents

Classification

Histological

It can occur in any fatty tissue (cutaneous or visceral) and is often diagnosed on the basis of a deep skin biopsy, and can be further classified by histological characteristics based on the location of the inflammatory cells (within fatty lobules or in the septa which separate them) and on the presence or absence of vasculitis.

There are thus four main histological subtypes:[3]

  1. lobular panniculitis without vasculitis (acute panniculitis, previously termed Weber-Christian disease,[4] systemic nodular panniculitis)
  2. lobular panniculitis with vasculitis
  3. septal panniculitis without vasculitis
  4. septal panniculitis with vasculitis

Symptomatic

Panniculitis can also be classified based on the presence or absence of systemic symptoms:

Associated conditions

Lipoatrophy or lipodystrophy (the loss of subcutaneous adipose tissue) can occur in any of these conditions.

See also

References

  1. ^ "panniculitis" at Dorland's Medical Dictionary
  2. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0. 
  3. ^ "Panniculitis. DermNet NZ". http://dermnetnz.org/dermal-infiltrative/panniculitis.html. Retrieved 2010-05-17. 
  4. ^ "eMedicine - Weber-Christian Disease : Article by Moise L Levy". http://www.emedicine.com/ped/topic2429.htm. Retrieved 2008-03-25. 
  5. ^ "eMedicine - Cold Panniculitis : Article by Geromanta Baleviciene". http://www.emedicine.com/derm/topic781.htm. Retrieved 2008-03-25. 

External links


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Look at other dictionaries:

  • panniculitis — Inflammation of subcutaneous adipose tissue. [panniculus + G. itis, inflammation] α1 antitrypsin deficiency p. multiple painful subcutaneous nodules occurring in patients with severe antitrypsin deficiency …   Medical dictionary

  • Panniculitis — Entzündung des Unterhaut Fettgewebes * * * Panniculitis   die, /... tiden, Entzündung des Unterhautfettgewebes (Panniculus adiposus) …   Universal-Lexikon

  • Panniculitis — Klassifikation nach ICD 10 M79.3 Pannikulitis, nicht näher bezeichnet …   Deutsch Wikipedia

  • panniculitis — pan·nic·u·li·tis …   English syllables

  • panniculitis — Weber Christian disease; n. inflammation of the layer of fat beneath the skin, leading to multiple tender nodules in the legs and trunk …   The new mediacal dictionary

  • panniculitis — pəˌnikyəˈlid.ə̇s noun ( es) Etymology: New Latin, from panniculus + itis : inflammation of the subcutaneous layer of abdominal fat …   Useful english dictionary

  • physical panniculitis — panniculitis caused by physical factors, such as cold or a physical trauma …   Medical dictionary

  • traumatic panniculitis — panniculitis, usually of the predominantly lobular type, caused by external trauma. Besides accidental blunt trauma, it may also be caused by cold (cold p.) or self induced trauma (factitial p.) …   Medical dictionary

  • Cytophagic histiocytic panniculitis — (CHP) was first described in 1980 by Winkelmann as a chronic histiocytic disease of the subcutaneous adipose tissue, which is characterized clinically by tender erythematous nodules, recurrent high fever, malaise, jaundice, organomegaly, serosal… …   Wikipedia

  • Cold panniculitis — is a skin condition characterized by inflammation of the subcutaneous fat after exposure to cold, most often seen in infants and young children.[1]:491 This condition has been described in children who suck ice or popsicles, and therefore is… …   Wikipedia

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