Tetrahydrozoline

Tetrahydrozoline

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ImageFile=Tetrahydrozoline.svg
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IUPACName=2-(1-tetralinyl)-4,5-dihydro-1H-imidazole
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Section1= Chembox Identifiers
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PubChem=5419
SMILES=C1CC(C2=CC=CC=C2C1)C3=NCCN3

Section2= Chembox Properties
Formula=C13H16N2
MolarMass=200.27954
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Section3= Chembox Hazards
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Tetrahydrozoline is a derivative of imidazoline, which is found in over-the-counter eye drops and nasal sprays. Other derivatives include naphazoline, oxymetazoline, and xylometazoline. Poisoning can result from an overdose.

Tetrahydrozoline is widely believed to cause violent diarrhea if administered orally, as in a few drops of Visine in an unsuspecting person's beverage. However, this is an urban legend, and the actual results may vary from severe nausea and vomiting to seizures or a coma. See Visine Prank. [ [http://www.snopes.com/medical/myths/visine.asp Urban Legends Reference Pages: Visine Prank ] ] Diarrhea is "not" a side effect.

Tetrahydrozoline is an alpha agonistcite journal |author=Dahlström M, Lindgren F, Berntsson K, "et al" |title=Evidence for different pharmacological targets for imidazoline compounds inhibiting settlement of the barnacle Balanus improvisus |journal=J. Exp. Zoolog. Part A Comp. Exp. Biol. |volume=303 |issue=7 |pages=551–62 |year=2005 |month=July |pmid=15945078 |doi=10.1002/jez.a.163 |url=http://dx.doi.org/10.1002/jez.a.163] and its main mechanism of action is the constriction of conjunctival blood vessels. This serves to relieve the redness of the eye caused by minor ocular irritants.

ee also

*Visine

References


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Look at other dictionaries:

  • tetrahydrozoline — /te treuh huy droz euh leen /, n. Pharm. a compound, C13H16N2, used in the treatment of nasal congestion and certain conditions of eye irritation. [TETRA + HYDRO 2 + (IMIDA)ZOL + INE2] * * * …   Universalium

  • tetrahydrozoline — noun A derivative of imidazoline used in eye drops and nasal sprays …   Wiktionary

  • tetrahydrozoline — /te treuh huy droz euh leen /, n. Pharm. a compound, C13H16N2, used in the treatment of nasal congestion and certain conditions of eye irritation. [TETRA + HYDRO 2 + (IMIDA)ZOL + INE2] …   Useful english dictionary

  • tetrahydrozoline hydrochloride — A sympathomimetic agent related to ephedrine, used as a topical nasal and conjunctival decongestant; chronic excessive use may convert an acute congestion into a chronic reactive hyperemia …   Medical dictionary

  • Тетрагидрозолин (Tetrahydrozoline) — лекарственное вещество, вызывающее сужение кровеносных сосудов; применяется для уменьшения отечности слизистой оболочки носа. См. Средство сосудосуживающее. Источник: Медицинский словарь …   Медицинские термины

  • ТЕТРАГИДРОЗОЛИН — (tetrahydrozoline) лекарственное вещество, вызывающее сужение кровеносных сосудов; применяется для уменьшения отечности слизистой оболочки носа. См. Средство сосудосуживающее …   Толковый словарь по медицине

  • Guanethidine — Systematic (IUPAC) name 2 [2 (azocan 1 yl)ethyl]guanidine Clinical data AHFS/Drugs.com …   Wikipedia

  • Visine — is a brand of eye drops produced by Johnson Johnson. Johnson Johnson acquired Visine, along with Pfizer s entire consumer healthcare portfolio, in December 2006.Visine Original The active ingredients in the original Visine formulation are… …   Wikipedia

  • Amphetamine — For other uses, see Amphetamine (disambiguation). Amphetamine Systematic (IUPAC) name …   Wikipedia

  • Dimethyltryptamine — Systematic (IUPAC) name 2 (1H indol 3 yl) N …   Wikipedia

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