David Graham (epidemiologist)

David Graham (epidemiologist)

David J. Graham, M.D., M.P.H., is an American epidemiologist who is currently the Associate Director of the Food and Drug Administration's Office of Drug Safety.

Graham has spent his career at the FDA studying the safety of drugs, many of them after approval using data from medical insurance companies. He claims successes in removing from the U.S. market the unsafe drugs Omniflox an antibiotic, Rezulin, a diabetes treatment, Fen-Phen and Redux, weight-loss drugs, and phenylpropanolamine, an over-the-counter decongestant, and in restricting the use of Trovan, an antibiotic, to use in hospitals. He also had a part in the removal of Lotronex, Baycol, Seldane, and Propulsid.

On November 18, 2004, Dr. Graham testified before the U.S. Senate Committee on Finance about Merck's withdrawal of the popular anti-inflammatory drug Vioxx the previous month because of serious safety concerns. In his testimony, he asserted his personal belief that the policies within the U.S. Food and Drug Administration were insufficient to protect the public from drugs which carry unacceptable risks, saying "I would argue that the FDA, as currently configured, is incapable of protecting America against another Vioxx. We are virtually defenseless."

After his testimony, Graham was publicly criticized by the FDA. He contacted the nonprofit Government Accountability Project, a whistleblower protection organization, for advice on getting his findings on Vioxx published over the objections of his superiors.

Recently, Graham and one of his FDA colleagues, Kate Gelperin, have called for the popular diabetes drug Avandia to be pulled from the market. Their study of the drug found possible evidence of an increased incidence of mortality; however, they found no indication of an increased risk of heart attack, contrary to other published studies.[1]

Notes

External links



Wikimedia Foundation. 2010.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • David Graham — may refer to: David Graham (photographer) (born 1952), American photographer David Graham (author) (1919–1994), pen name of British writer Robert Hale David Graham (footballer born 1978), Scottish footballer David Graham (footballer born 1983),… …   Wikipedia

  • David Skegg — Sir David Christopher Graham Skegg, KNZM, OBE, FRSNZ (born 1947) is a New Zealand epidemiologist and university administrator. He is a former Vice Chancellor of the University of Otago and Professor of Preventive and Social Medicine. His primary… …   Wikipedia

  • Health and Disease — ▪ 2009 Introduction Food and Drug Safety.       In 2008 the contamination of infant formula and related dairy products with melamine in China led to widespread health problems in children, including urinary problems and possible renal tube… …   Universalium

  • 1946 in Australia — Infobox Australian year monarch = George VI governor general = Prince Henry, Duke of Gloucester pm =Ben Chifley population = 7,465,157 australian = elections =Federal, TAS See also: 1945 in Australia, other events of 1946, 1947 in Australia and… …   Wikipedia

  • MacArthur Fellows Program — For the award in the field of ecology, see Robert H. MacArthur Award. The MacArthur Fellows Program or MacArthur Fellowship (nicknamed the Genius Award) is an award given by the John D. and Catherine T. MacArthur Foundation each year to typically …   Wikipedia

  • List of English people — This is a partial list of English people of note and of some notable individuals born in England, alphabetically within categories.Actors and actresses*Dame Julie Andrews (born 1935) *Naveen Andrews (born 1969) *Gabrielle Anwar (born 1970) *Rowan …   Wikipedia

  • Roberts (surname) — Roberts derives from the Saxon/Norman given name Robert, meaning bright fame ndash; from the Germanic elements hrod meaning fame and beraht meaning bright. Robert may also mean Son of Robert .Fact|date=September 2007 The name is common in both… …   Wikipedia

  • List of physicians — This is a list of famous physicians in history: Contents 1 Physicians famous for their role in advancement of medicine 2 Physicians famous chiefly as eponyms 3 Physicians famous as criminals …   Wikipedia

  • Contagion (film) — Contagion Theatrical release poster Directed by Steven Soderbergh …   Wikipedia

  • Deaths in August 2010 — Contents 1 August 2010 1.1 31 1.2 30 1.3 29 …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”